論文

2024年

: Yuki Shin, Shunpei Maruyama, Kohei Kawasaki, Keito Aoi, Kohshin Washiyama, Ichiro Nishinaka, Shinya Yano, Hiromitsu Haba and Akihiko Yokoyama; Journal of Radioanalytical and Nuclear Chemistry 333, 403-409 (2024).

Production of Auger-electron-emitting ^103mRh via a ¹⁰³Pd/^103mRh generator using an anion-exchange resin: Tomoyuki Ohya, Jun Ichinose, Kotaro Nagatsu, Yumi Sugo, Noriko Ishioka, Hiroshi Watabe, Masatoshi Itoh, Katsuyuki Minegishi and Ming-Rong Zhang; Radiochimica Acta 112, 37-43 (2024).

Development and Utility of an Imaging System for Internal Dosimetry of Astatine-211 in Mice: Atsushi Yagishita, Miho Katsuragawa, Shin’ichiro Takeda, Yoshifumi Shirakami, Kazuhiro Ooe, Atsushi Toyoshima, Tadayuki Takahashi and Tadashi Watabe; Bioengineering 11, 25 (2024).

: Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuichiro Kadonaga, Tadashi Watabe, Kazuhiro Ooe, Xiaojie Yin, Hiromitsu Haba, Kenji Shirasaki, Hidetoshi Kikunaga, Kazuaki Tsukada, Atsushi Toyoshima,Jens Cardinale, Frederik L.Giesel and Koichi Fukase; International Journal of Molecular Sciences 25, 933 (2024).

: Soichi Ando, Toshihiko Fujimoto, Mizuki Sudo, Shoichi Watanuki, Kotaro Hiraoka, KazukoTakeda, Yoko Takagi, Daisuke Kitajima, Kodai Mochizuki, Koki Matsuura, Yuki Katagiri,Fairuz Mohd Nasir, Yuchen Lin, Mami Fujibayashi, Joseph T. Costello, Terry McMorris, YoichiIshikawa, Yoshihito Funaki, Shozo Furumoto, Hiroshi Watabe, Manabu Tashiro; Journal of Physiology 602, 3 (2024).

2022年

Tumor targeting of ²¹¹At-labeled antibody under sodium ascorbate protection against radiolysis: Hiroki Takashima, Kazunobu Ohnuki, Shino Manabe, Yoshikatsu Koga, Ryo Tsumura, Takahiro Anzai, Yang Wang, Xiaojie Yin, Nozomi Sato and Yudai Shigekawa; Molecular Pharmaceutics 20, 2 (2022).

Protection from contamination by ²¹¹At, an enigmatic but promising alpha‑particle‑emitting radionuclide: Kazunobu Ohnuki, Mitsuyoshi Yoshimoto, Hiromitsu Haba, Shino Manabe, Hiroki Takashima, Masahiro Yasunaga, Yasumasa Takenaka and Hirofumi Fujii; EJNMMI Physics 9, 39 (2022).

A pure tungsten collimator manufactured using 3D printing technology for the evaluation of ²¹¹At radionuclide therapy: Hirofumi Fujii, Kazunobu Ohnuki, Shin’ichiro Takeda, Miho Katsuragawa, Atsushi Yagishita, Goro Yabu, Shin Watanabe and Tadayuki Takahashi; RADIOISOTOPES 71, 141-151 (2022).

The safe handling of ²¹¹At compounds: Kazunobu Ohnuki, Yasumasa Takenaka, Mitsuyoshi Yoshimoto and Hirofumi Fujii; Annals of Nuclear Medicine 36, 842-843 (2022).

Ionic liquid extraction of astatine for a nuclear medical utilization: Y. Nagai, K. Aoi, S. Maruyama, A. Yokoyama, K. Washiyama, I. Nishinaka, Y. Wang, X. Yin, A. Nambu, Y. Shigekawa, and H. Haba; RIKEN Accelerator Progress Report 55, 135 (2022).

What Caused Declines in Intertidal Invertebrate Populations around Fukushima Daiichi Nuclear Power Plant after the 2011 Great East Japan Earthquake, Tsunami, and Nuclear Disaster?: Toshihiro Hiroguchi and Keita Kodama; Toxics 10, 214 (2022).

Estimated Isotopic Compositions of Yb in Enriched ¹⁷⁶Yb for Producing ¹⁷⁷Lu with High Radionuclide Purity by ¹⁷⁶Yb(d,x)¹⁷⁷Lu: Yasuki Nagai , Masako Kawabata , Shintaro Hashimoto, Kazuaki, Tsukada , Kazuyuki, Hashimoto and Shoji Motoishi; Jornal of the Physical Sciety of Japan 91, 044201 (2022).

Potassium transporter KUP9 participates in K⁺ distribution in roots and leaves under low K⁺ stress: Taro Yamanashi, Takeshi Uchiyama, Shunya Saito, Taiki Higashi, Hayato Ikeda, Hidetoshi Kikunaga, Mutsumi Yamagami, Yasuhiro Ishimaru and Nobuyuki Uozumi; Stress Biology 2, 52 (2022).

2021年

Neopentyl glycol as a scaffold to provide radiohalogenated theranostic pairs of high in vivo stability: Hiroyuki Suzuki, Yuta Kaizuka, Maho Tatsuta, Hiroshi Tanaka, Nana Washiya, Yoshifumi Shirakami, Kazuhiro Ooe, Atsushi Toyoshima, Tadashi Watabe, Takahiro Teramoto, Ichiro Sasaki, Shigeki Watanabe, Noriko S. Ishioka, Jun Hatazawa, Tomoya Uehara, and Yasushi Arano; Journal of Medicinal Chemistry 64, 15846-15857 (2021).

Extended single-dose toxicity study of [²¹¹At]NaAt in mice for the first-in-human clinical trial of targeted alpha therapy for differentiated thyroid cancer: Tadashi Watabe, Kazuko Kaneda-Nakashima, Kazuhiro Ooe, Yuwei Liu, Kenta Kurimoto, Takashi Murai, Yuka Shidahara, Kenji Okuma, Masanori Takeuchi, Masayuki Nishide, Atsushi Toyoshima, Atsushi Shinohara & Yoshifumi Shirakami; Annals of Nuclear Medicine 35, 702-718 (2021).

Intratumoral administration of astatine-211-labeled gold nanoparticle for alpha therapy: Hiroki Kato, Xuhao Huang, Yuichiro Kadonaga, Daisuke Katayama, Kazuhiro Ooe, Atsushi Shimoyama, Kazuya Kabayama, Atsushi Toyoshima, Atsushi Shinohara, Jun Hatazawa & Koichi Fukase; Journal of Nanobiotechnology 19, 223 (2021).

Preparation of a carrier free ¹²⁴Sb tracer produced in the Sn (p, n) reaction: Naoki Miyazawa, Masaki Uesugi and Akihiko Yokoyama; Radiochimica Acta 109, 453-458 (2021).

Radioimmunotherapy with an ²¹¹At-labeled anti-tissue factor antibody protected by sodium ascorbate: Hiroki Takashima, Yoshikatsu Koga, Shino Manabe, Kazunobu Ohnuki, Ryo Tsumura, Takahiro Anzai, Nozomi Iwata, Yang Wang, Takuya Yokokita, Yukiko Komori, Daiki Mori, Sachiko Usuda, Hiromitsu Haba, Hirofumi Fujii, Yasuhiro Matsumura, Masahiro Yasunaga; Cancer Science 112, 1975-1986 (2021).

Stabilization of an ²¹¹At-Labeled Antibody with Sodium Ascorbate: Shino Manabe, Hiroki Takashima, Kazunobu Ohnuki, Yoshikatsu Koga, Ryo Tsumura, Nozomi Iwata, Yang Wang, Takuya Yokokita, Yukiko Komori, Sachiko Usuda, Daiki Mori, Hiromitsu Haba, Hirofumi Fujii, Masahiro Yasunaga, and Yasuhiro Matsumura; ACS Omega 6, 14887-14895 (2021).

Synthesis of [²¹¹At]4-astato-L-phenylalanine by dihydroxyboryl-astatine substitution reaction in aqueous solution: Yoshifumi Shirakami, Tadashi Watabe, Honoka Obata, Kazuko Kaneda, Kazuhiro Ooe, Yuwei Liu, Takahiro Teramoto, Atsushi Toyoshima, Atsushi Shinohara, Eku Shimosegawa, Jun Hatazawa & Koichi Fukase; Scientific Reports 11, 12982 (2021).

Image reconstruction method for dual-isotope positron emission tomography: T. Fukuchi, M. Shigeta, H. Haba, D. Mori, T. Yokokita, Y. Komori, S. Yamamoto and Y. Watanabe; Journal of Instrumentation 16, P01035 (2021).

Emitting cancer therapy using ²¹¹At-AAMT targeting LAT1: Kazuko Kaneda-Nakashima, ZiJian Zhang, Yoshiyuki Manabe, Atsushi Shimoyama, Kazuya Kabayama, Tadashi Watabe, Yoshikatsu Kanai, Kazuhiro Ooe, Atsushi Toyoshima, Yoshifumi Shirakami, Takashi Yoshimura, Mitsuhiro Fukuda, Jun Hatazawa, Takashi Nakano, Koichi Fukase, Atsushi Shinohara; Cancer Science 112, 1132-1140 (2021).

2020年

Preclinical Evaluation of Radiation-Induced Toxicity in Targeted Alpha Therapy Using [(²¹¹)At] NaAt in Mice: Yuwei Liua,Tadashi Watabe, Kazuko Kaneda-Nakashima, Kazuhiro Ooe, Yoshifumi Shirakami, Atsushi Toyoshima, Eku Shimosegawa ,Takashi Nakano, Atsushi Shinohara, Jun Hatazawa; Translational Oncology 13, 100757 (2020).

Performance demonstration of a hybrid Compton camera with an active pinhole for wide-band X-ray and gamma-ray imaging: Akihisa Omata, Jun Kataoka, Kazuya Fujieda, Shogo Sato, Eri Kuriyama, Hiroki Kato, Atsushi Toyoshima, Takahiro Teramoto, Kazuhiro Ooe, Yuwei Liu, Keiko Matsunaga, Takashi Kamiya, Tadashi Watabe, Eku Shimosegawa & Jun Hatazawa; Scientific Reports 10, 14064 (2020).

2019年

Dispersal rates of astatine-211 from aqueous solutions and chloroform: Atsushi TOYOSHIMA, Kojiro NAGATA, Kazuhiro OOE, Zijian ZHANG, Takumi IKEDA, Soichiro ICHIMURA, Honoka OBATA, Takashi YOSHIMURA, Atsushi SHINOHARA; Radiation Safety Management 18, 16-22 (2019).

Activities of the Consortium for Medicine, Chemistry, and Physics at Osaka University: Kazuya Kabayama, Kazuko Kaneda, Atsushi Shinohara, Yoshifumi Shirakami, Tadashi Watabe, Zijian Zhang, Atsushi Toyoshima, Takashi Yoshimura, Yoshiyuki Manabe, Atsushi Shimoyama, Koichi Fukase; Journal of Medical Imaging and Radiation Sciences 50, S40 (2019).

2017年

Assessment of ^43,44Sc isotope production in proton- and alpha- induced reactions: C. Rangacharyulu, M. Fukuda, H. Kanda, S. Nishizaki & N. Takahashi; Journal of Radioanalytical and Nuclear Chemistry 314, 1967-1971 (2017).

A One-Pot Three-Component Double-Click Method for Synthesis of [⁶⁷Cu]-Labeled Biomolecular Radiotherapeutics: Katsumasa Fujiki, Shinya Yano, Takeshi Ito, Yuki Kumagai, Yoshinori Murakami, Osamu Kamigaito, Hiromitsu Haba & Katsunori Tanaka; Scientific Reports 7, 1912 (2017).

2016年

In vivo visualization of tau deposits in corticobasal syndrome by ¹⁸F-THK5351 PET: Akio Kikuchi, Nobuyuki Okamura, Takafumi Hasegawa, Ryuichi Harada, Shoichi Watanuki, Yoshihito Funaki, Kotaro Hiraoka, Toru Baba, Naoto Sugeno, Ryuji Oshima, Shun Yoshida, Junpei Kobayashi, Michinori Ezura, Michiko Kobayashi, Ohito Tano, Shunji Mugikura, Ren Iwata, Aiko Ishiki, Katsutoshi Furukawa, Hiroyuki Arai, Shozo Furumoto, Manabu Tashiro, Kazuhiko Yanai, Yukitsuka Kudo, Atsushi Takeda, Masashi Aoki; Neurology 87, 2309-2316 (2016).

プレスリリース

2024年

難治性前立腺がんに対する医師主導治験を開始: 渡辺直史; 大阪大学 5月27日, (2024).

2023年

膵臓がんを画像で描出し、アルファ線で攻撃: 渡辺直史; 大阪大学 10月16日, (2023).

塩害から種子形成を保護するナトリウム輸送体: 魚住信之; 東北大学 6月5日, (2023).

著書

2023年

越川七星, 片岡純: 薬物動態を可視化する放射化イメージング　ー宇宙の元素合成を医療へ応用 . 月刊化学 48, pp.33-37: 化学同人, (2023).

2022年

飯田康彦:第7章治療研究（β線放出核種） . 放射性衣料品開発研究への招待, （間賀田泰寛編, 70p.） pp.44-49: 日本アイソトープ協会, (2022).