• 日時：2024年5月16日（木）15：10-17：00
• 場所：理学研究科D308教室

発表者：黛 功樹さん（化学専攻）
タイトル：Development of novel drugs using the alpha-particle emitting nuclide, At-211, and their application to cancer immunotherapy
アブストラクト：
In recent years, Targeted Radioisotope Therapy (TRT) has attracted a great deal of attention. Among them, targeted alpha therapy (TAT) using alpha-particle emitting radionuclides has been developing rapidly. I am conducting research using At-211, an alpha-particle emitting nuclide with a short half-life of 7.2 hours, which can be manufactured domestically, and is expected to be used in TAT. In this presentation, I present the development of At-211-labeled drugs and the elucidation of the immune activity mechanism induced when cancer cells are injured by At-211.

発表者：Jinyuan DUNさん（物理学専攻）
タイトル：L-SHELL OPACITY MEASUREMENT EXPERIMENT AT GEKKO/LFEX FACILITY
アブストラクト：
Abstract:
Opacity is an important parameter in high energy density physics, which controls the process of radiation energy transfer in the plasma. Understanding the atomic process in stellar interior conditions depends on the opacities of mid-atomic-number elements over a wide range of temperatures, which can also help us to evaluate the efficiency of inertial confinement fusion.
However, the complexity of the opacity model makes it easy to ignore some of the details of the radiative transfer process, which leads to inaccurate predictions. For example, one of the possible explanations for the disagreement between solar models and helioseismology observation is insufficient theoretical opacities. The experimental approach, for validation of the opacity models, is crucial for the HED research.
The systematic study on opacities for different elements by Sandia National Laboratories (SNL) shows that the plasma with an open L-shell structure mainly contributes to the disagreements. The study proposes a hypothesis that the existing opacity models are missing some important physics processes that become significant at stellar interior conditions.
Here we present the works that have been done toward the verification of the hypothesis above and the prospects for future research.